Discussion In this double-blind, randomized research, the combination of nivolumab and ipilimumab led to a significantly higher objective response rate, even more frequent complete responses, and significantly longer progression-free survival than ipilimumab alone among untreated patients with advanced melanoma previously. Based on the high degree of tumor decrease in the current study, with a high rate of complete responses , a favorable clinical benefit can be anticipated with much longer follow-up.Diabetes can be managed through the use of diabetes medicines, making essential lifestyle changes related to diet and exercise, and monitoring blood sugar and HbA1c amounts. ‘When diabetes is not managed properly, it can result in damage of essential systems in the physical body, including the heart, kidneys, and eyes, and cause life-threatening complications actually,’ said Brian Blaser , executive vice president, Diagnostics Products, Abbott. ‘With the CE Tag of Abbott's ARCHITECT clinical chemistry HbA1c test, we are very happy to offer this valuable tool to greatly help doctors diagnose diabetes and identify individuals at-risk for developing diabetes. Doctors can use this given information to boost patient care.’ The ARCHITECT clinical chemistry HbA1c test is available in many countries throughout Europe, Asia, Latin America, Canada and Africa, pending country registration.