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Bone reduction is an important feature of the model, related to renal osteodystrophy seen in CKD individuals. Recombinant AC-200 or automobile control were administered for two weeks by intravenous shots to 5/6 Nx rats. Urine and Serum biochemistry assays were performed to look for the effects on renal function and mineral metabolism. Femurs had been analyzed by X-ray and histology to determine results on both cortical and trabecular bone. Related StoriesPresence of connexin proteins suppresses principal tumor growthDiscovery could offer clues to how some infections control expression of genetic materialResearchers successfully repair nerve cell damage in Alzheimer's dementiaAC-200 administration resulted in marked reductions in serum phosphorus and PTH levels in comparison to those in automobile treated controls.