Over time, the problem can prove fatal. Smoking is the main cause of COPD, and a lot more than 70 % of people with the condition are past or current smokers, the task force noted. The most important step you can take to prevent COPD is in order to avoid smoking, Phillips said. People who smoke should talk to their doctors about ways to quit. Another expert agreed. The chance of developing COPD in smokers could possibly be greatly curtailed by helping them to give up smoking through behavioral modifications, practical counseling, medicine, nicotine-replacement therapy, and access to community resources, said Dr.The first writer and two authors who are workers of Amgen take primary responsibility for the info and analyses and for the fidelity of the analysis to the process. The first writer wrote the 1st draft of the manuscript with editorial support from Amgen. All of the authors contributed to subsequent drafts of the manuscript and made the decision to submit the manuscript for publication. Clinical-trial agreements between Amgen and the investigators included provisions relating to confidentiality of the study data, a practice that is standard for scientific trials in the development phase of fresh pharmaceutical agents.5 or more at each of the three sites).